The Art of Biostimulation: A Journey Around the Eyes and Lips
When the fat pads in your mid-face begin to drop, and a little weight loss reveals a hollowness under the eyes—along with a deepening of the nasolabial fold area—it's time to think about restoring structure. The goal is to strengthen the area around the eyes with a targeted biostimulating treatment, using a combination of mesotherapy and thread placement. The product chosen for the eye area is Curanex Eye, a lightweight PDRN-based formula designed to brighten, hydrate, and improve skin texture. This polynucleotide, derived from salmon DNA (specifically from rainbow trout), is well known for its ability to target dark circles, fine lines, and the creeping thinness that develops with age. The injection is done with a meso needle, using a fine syringe to place the product precisely where it's needed most.
For the lips and the vermilion border, the approach is different: twenty mono threads are placed to help firm, lift, and stimulate collagen in this delicate area. These are 30-gauge, 25-millimeter PCL threads—single filaments that are remarkably easy to work with. The 25-millimeter length is ideal for beginners, because as you push a thread through the skin, your face bends, and longer threads can be harder to keep in a consistent plane. A 25-millimeter thread locks in the tail very well, unlike the shorter 12-millimeter threads. The 12 millimeter threads often have the tail pop out because the needle is too short for the filament, leading to a lot of loss and frustration. So if you are learning threads for the first time, the 25-millimeter monofilament is highly recommended.
Before any procedure, preparation is key. The face is washed, then derma rolled to help the numbing cream penetrate. A thick layer of lidocaine cream is applied, and then covered with plastic wrap cut into sections—one for the eyelid, one for the under-eye area, one for above and below the lips. This way, the numbing cream can be removed section by section as you work, keeping the rest of the face numb for longer. It is common for the lips to become completely numb, and even some cream may get into the mouth; that is fine, it is safe. The numbing cream then sits for about an hour before the live session begins.
Once numb, the procedure starts with the lips because they are the most annoying area. The hands are sanitized, and the sterile package of threads is opened. Inside a Queen package, you get two packages of ten threads each. You can use ten in one session and ten later, but once a package is opened, the threads must be used—they go bad over time. For this session, both packages are opened to use all twenty. The threads are kept on the right-hand side, and used ones are discarded to the left, so there is no confusion. Each thread is inserted along the vermilion border, aiming to end right at the peak of the lip. The needle is inserted with a slight arc, pushing the base so that the tip stays shallow. You can see the thread traveling under the skin, and once the base is reached, the tail is fully inserted. Then the needle is twisted and removed, leaving no thread tail. Running a finger along the edge confirms everything is smooth. Three threads are placed above the lip, two in each nasolabial fold, three stacked underneath, and two in the lines near the eyes.
After the threads, the Curanex Eye is injected using meso needles. The product comes in a needleless syringe, so fine meso needle tips are attached for precise placement around the eyes. The injection creates small blebs under the skin. A bruise may appear—sometimes a significant one—but immediate ice and compression help. The first morning after the treatment, the eyes can be very swollen, even if there is no major bruise. The product seems to sit in the area and activate for a while, causing edema. This can be alarming, but it is temporary and goes down. Using an LED mask multiple times the first evening helps soothe the area.
Within four to five days, the bruise fades significantly. In less than a week, the worst bruise is almost completely healed, and the lips are fully healed. Some people heal faster naturally, but the combination of the LED mask and the body's own response works well. The treatment is a way to build collagen in areas that have lost volume and definition, and the results are subtle yet long-term as the threads dissolve and the polynucleotide stimulates repair. The key is to map everything out ahead of time on a face chart, noting the date, procedure, and product used, so you can track your progress over time.